Maryland's Defense Patent Database

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Vaccine for transcutaneous immunization

Patent image
MRDC

A vaccine delivered by transcutaneous immunization provides an effective treatment against infections by pathogens such as, for example, enterotoxigenic Escherichia coli (ETEC) and/or for symptoms of diarrheal disease caused thereby. For example, one, two, three, four, five or more antigens derived from ETEC and capable of inducing an antigen-specific immune response (e.g., toxins, colonization or virulence factors) and one or more optional adjuvant (e.g., whole bacterial ADP-ribosylating exotoxins, B subunits or toxoids thereof, detoxified mutants and derivatives thereof) are used to manufacture vaccines or to induce systemic and/or mucosal immunity.

Inventors: 
Glenn, Gregory M.; Cassels, Frederick J.
Patent Number: 
Technical domain: 
Materials and Coatings
FIle Date: 
2002-02-13
Grant Date: 
2009-05-05
Grant time: 
2,638 days
Grant time percentile rank: 
48
Claim count percentile rank: 
5
Citations percentile rank: 
17
'Cited by' percentile rank: 
1
Assignee: 
US ARMY