Maryland's Defense Patent Database

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Protein vaccines against poxviruses

Patent image
MRDC

The invention described here entails a protein vaccine against poxviruses which contains at least two purified recombinant monkeypox virus proteins or peptides. The proteins or peptides are encoded by the open reading frames of the monkeypox ortholog genes M1R, A35R, A29L B6R, and orthologs of these proteins or peptides having 90% identity. The invention also entails a vaccine protocol against poxvirus whereby a vaccine is vaccinated with a first vaccine made up of a nucleic acid vaccine of three or more poxvirus virus genes, and subsequently vaccinated with at least one other booster vaccine made up of two or more poxvirus virus proteins.

Inventors: 
Hooper, Jay W.; Franchini, Genoveffa
Patent Number: 
Technical domain: 
Materials and Coatings
FIle Date: 
2006-09-20
Grant Date: 
2010-09-07
Grant time: 
1,448 days
Grant time percentile rank: 
26
Claim count percentile rank: 
4
Citations percentile rank: 
1
'Cited by' percentile rank: 
1
Assignee: 
US ARMY