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Amino acid sites in Flavivirus E proteins useful for development of diagnostics and vaccines

Patent image
AECBC

Highly immunoreactive viral peptides are disclosed which are derived from the E protein of major groups of the Flavivirus genus by computational analyses. These peptides are used in reliable diagnostic methods for the detection and diagnosis of Flavivirus, detecting the presence of antibodies against Flavivirus, and to form vaccine composition(s) for the prevention of Flavivirus infections in humans.

Inventors: 
Sagripanti, Jose-luis; Mazumder, Raja; Wu, Cathy Huey-hwa
Patent Number: 
Technical domain: 
Biotechnology and Healthcare
FIle Date: 
2008-04-02
Grant Date: 
2011-05-17
Grant time: 
1,140 days
Grant time percentile rank: 
20
Claim count percentile rank: 
3
Citations percentile rank: 
1
'Cited by' percentile rank: 
1
Assignee: 
UNITED STATES OF AMERICA