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A tamper-evident cargo seal is disclosed, comprising a pin that is passed through a hasp on a shipping container, a body member, a pair of parallel guide members, at least one security label blank, and a cover. One end of the pin is keyed. The body member has a slot through a side surface extending into the interior, and is keyed to receive the pin. Abutting the top surface of the body member are two parallel guide members, bounding an area comprising the top surface of the body member. One of the guide members also has a slot to allow the pin to engage the slot in the body member. One or two removable security label blanks are inserted between the guides after the pin is inserted into the slot, and a security label is affixed over the blanks. A cover engages the body and guide members to protect the label.