Maryland's Defense Patent Database

The defense community in Maryland is an R&D powerhouse.

Use this database to see the innovative patents that are poised for commercialization.

Rapid and sensitive method to measure endonuclease activity

Patent image
CCDC CBC

A rapid and sensitive method to measure endonuclease activity comprising reacting a substrate suspected of having endonuclease activity with a synthetic nucleotide to induce endonuclease cleavage of the synthetic nucleotide followed by measurement of activity by carrying out a polymerase chain reaction (PCR). When no polymerase chain reaction takes place when carrying out the method it is indicative of no endonuclease activity in the substrate. Synthetic oligonucleotides, primers, and probes useful for carrying out the method are disclosed.

Inventors: 
Dorsey, Russell M.; Dorsey, Robert W.
Patent Number: 
Technical domain: 
Biotechnology and Healthcare
FIle Date: 
2008-11-12
Grant Date: 
2012-03-06
Grant time: 
1,210 days
Grant time percentile rank: 
22
Claim count percentile rank: 
1
Citations percentile rank: 
1
'Cited by' percentile rank: 
1
Assignee: 
UNITED STATES OF AMERICA