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Methods for detecting Venezuelan equine encephalitis virus TC-83 and its use as a biological agent simulant

Patent image
AECBC

The present invention is generally related to products and methods that facilitate the use of Venezuelan equine encephalitis (VEE) virus TC-83 (TC-83) as a non-hazardous simulant, or surrogate, for viable pathogenic viruses. Specifically, TC-83 nucleic sequences are used in a method of detecting VEE or TC-83 in a sample thought to contain a biological threat agent. TC-83 and its nucleic acid sequence may therefore be used in the research, development, testing, evaluation, and training for technologies that enable the detection of biological threat agents. More particularly, specific primers and probes may be used to verify that instruments and systems using PCR detection methods are functioning properly.

Inventors: 
Horsmon, Jennifer R.; O'connell, Kevin P.
Patent Number: 
Technical domain: 
Biotechnology and Healthcare
FIle Date: 
2008-01-09
Grant Date: 
2012-05-01
Grant time: 
1,574 days
Grant time percentile rank: 
28
Claim count percentile rank: 
3
Citations percentile rank: 
1
'Cited by' percentile rank: 
1
Assignee: 
UNITED STATES OF AMERICA