Maryland's Defense Patent Database

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Spectro-temporal optical encoding of information using a time-gated fluorescence resonance transfer (FRET)

Patent image
NRL

Described herein is a time-gated, two-step FRET relay effective to provide temporal transference of a prompt FRET pathway, or provide spectro-temporal encoding analytical signals and other information. A FRET relay assembly includes a long lifetime FRET donor (for example, a lanthanide complex), a semiconductor quantum dot (QD) configured as an intermediate acceptor/donor in FRET, and a fluorescent dye configured as a terminal FRET acceptor, wherein the long lifetime FRET donor has an excited state lifetime of at least one microsecond and the QD and fluorescent dye each have excited state lifetimes of less than 100 nanoseconds.

Inventors: 
Algar, Russ W.; Hildebrandt, Niko; Huston, Alan L.; Medintz, Igor L.
Patent Number: 
Technical domain: 
Biotechnology and Healthcare
FIle Date: 
2012-05-18
Grant Date: 
2013-07-02
Grant time: 
410 days
Grant time percentile rank: 
7
Claim count percentile rank: 
2
Citations percentile rank: 
1
'Cited by' percentile rank: 
1
Assignee: 
US NAVY