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Unique calibrator polynucleotides and methods of using in quantitative nucleic acid assays

Patent image
AMRMC

Disclosed herein are polynucleotides which may be used to calibrate or standardize quantitative nucleic acid assays. As disclosed, the polynucleotides comprise a sequence derived from a plant viroid polynucleotide or a bacterial or chloroplast Type II intron polynucleotide. Also disclosed are methods of making and using the polynucleotides.

Inventors: 
Phillips, Christopher S.; Ruff, Albert L.; Dillman III, James F.
Patent Number: 
Technical domain: 
Biotechnology and Healthcare
FIle Date: 
2008-07-10
Grant Date: 
2014-02-04
Grant time: 
2,035 days
Grant time percentile rank: 
37
Claim count percentile rank: 
2
Citations percentile rank: 
1
'Cited by' percentile rank: 
1
Assignee: 
US ARMY