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Control of protein activity using a conducting polymer

Patent image
NRL

A device having a substrate and an enzyme attached to the substrate. The substrate has a polymeric surface having at least two conductivity states. A minimum voltage that does not cause a redox reaction in the enzyme may be applied to the polymeric surface to change the conductivity state of the surface. A method of controlling enzyme activity by providing the above substrate with polymeric surface, attaching an enzyme to the substrate, and altering the conductivity state of the polymeric surface. Changing the conductivity of the polymer can change the activity of the enzyme.

Inventors: 
Martin, Brett D.; Velea, Luminita M.; Ratna, Banahalli; Gaber, Bruce P.
Patent Number: 
Technical domain: 
Biotechnology and Healthcare
FIle Date: 
2005-08-11
Grant Date: 
2014-04-29
Grant time: 
3,183 days
Grant time percentile rank: 
58
Claim count percentile rank: 
3
Citations percentile rank: 
1
'Cited by' percentile rank: 
1
Assignee: 
US NAVY