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Human monoclonal antibodies protective against bubonic plague

Patent image
AMRMC

In this application are described fully human monoclonal antibodies which specifically recognize F1 or V antigen of Y. pestis and epitopes recognized by these monoclonal antibodies. Also provided are mixtures of antibodies of the present invention, as well as methods of using individual antibodies or mixtures thereof for the detection, prevention, and/or therapeutical treatment of plague infections in vitro and in vivo.

Inventors: 
Amemiya, Kei; Dimitrov, Dimiter S.; Xiao, Xiaodong
Patent Number: 
Technical domain: 
Biotechnology and Healthcare
FIle Date: 
2010-04-08
Grant Date: 
2014-05-13
Grant time: 
1,496 days
Grant time percentile rank: 
27
Claim count percentile rank: 
5
Citations percentile rank: 
1
'Cited by' percentile rank: 
1
Assignee: 
US ARMY