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Non-wild-type organophosphorus acid anhydrolases for enzymatic decontamination

Patent image
AECBC

Provided are non-wild-type organophosphorus acid anhydrolases that are capable of degrading (ethyl {2-[bis(propan-2-yl)amino]ethyl}sulfanyl) (methyl)phosphinate and other V-agents. Particular embodiments include an organophosphorus acid anhydrolase including an amino acid substitution at position 212.

Inventors: 
Shah, Saumil S.; Guelta, Mark A.; Harvey, Steven P.
Patent Number: 
Technical domain: 
Biotechnology and Healthcare
FIle Date: 
2013-12-17
Grant Date: 
2015-04-28
Grant time: 
497 days
Grant time percentile rank: 
9
Claim count percentile rank: 
2
Citations percentile rank: 
1
'Cited by' percentile rank: 
1
Assignee: 
UNITED STATES OF AMERICA