Maryland's Defense Patent Database

The defense community in Maryland is an R&D powerhouse.

Use this database to see the innovative patents that are poised for commercialization.

Adhesin as immunogen against enterotoxigenic <i>Escherichia coli</i>

Patent image
NMRC

The inventive subject matter relates to the methods for the induction of immunity and prevention of diarrhea resulting from Escherichia coli. The inventive subject matter also relates to the use Escherichia coli adhesins as immunogens and to the construction of conformationally stability and protease resistant Escherichia coli adhesin constructs useful for inducing immunity to Escherichia coli pathogenic bacteria. The methods provide for the induction of B-cell mediated immunity and for the induction of antibody capable of inhibiting the adherence and colonization of Escherichia coli including enterotoxigenic Escherichia coli, to human cells.

Inventors: 
Savarino, Stephen J.
Patent Number: 
Technical domain: 
Biotechnology and Healthcare
FIle Date: 
2006-01-10
Grant Date: 
2015-07-14
Grant time: 
3,472 days
Grant time percentile rank: 
63
Claim count percentile rank: 
2
Citations percentile rank: 
1
'Cited by' percentile rank: 
1
Assignee: 
US NAVY